September 1, 2022. Cala Health published the results of long term use of the Cala Trio for the treatment of Essential Tremors of the hand/forearm. The study included 321 individuals who used the Cala Trio for at least 90 days between August 2019 through June 2021.
This study compared the before and after measurement of tremor amplitude in a 20 second postural hold. 59% of the group had a 50% reduction in the measured tremor amplitude power. This compares favorably with the best pharmacological treatment of Essential Tremors.
Patients with severe tremors experienced the greatest reduction in their tremors from this treatment.
No significant habituation was observed in patients who use the Cala Trio for more than one year.
In a voluntary survey, patients reported improvements in three areas of activities of daily living: eating 74%, drinking 65%, writing 64%. 65% of the survey preferred treatment with the Cala Trio over both medication and surgical intervention.
The full paper can be found here.
James Being the technical guy that you are I thought you might find this device (at the following link) and the theory behind it quite fascinating. I think I might try to give your device a go.
ReplyDeleteTom C
If you decide to try out my device, let me know and it is still a work in progress.
DeleteJames Waiting for the parts to arrive to build the stimulater. I already have a TENS unit. My unit has several setting on it.
DeletePulse width, pulse rate and then a separate intensity control for each of the two channels. How did you determine what these setting should be. Was it a matter of trial and error?
Tom C
The best source is Cala: "Stimulation consisted of a series of charge balanced biphasic pulses, 300 μs biphasic pulses, with a 50 μs interpulse period between pulses, delivered at a frequency of 150 Hz. The stimulation alternated between the median and radial nerve at a frequency equal to tremor frequency as measured by on‐board accelerometers (for example, for a measured 5 Hz tremor frequency, stimulation was applied over the median nerve for 100 msec and then was applied over the radial nerve for 100 msec)"
Deletecite
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427656/
As for intensity, start low and gradually increase it to a level that you can tolerate. My TENS unit has a scale of 1-50. I never get above 20. Most of the time I use a setting of 8-10.
James
DeleteThanks for the info. I'll be shopping for a new TENS unit since mine only delivers a monophasic pulse. Also looks like my switching relay won't be here until beginning of January so I'll be limited to monitoring my tremor until that arrives.
Tom C
Maybe we should move this conversation over to Reddit: https://www.reddit.com/r/EssentialTremorLab/ That's where I host most of the technical talk and there is a Chat facility if you perfer.
DeleteThat makes sense. Will move it to the lab on Reddit
Deletethx
DeleteJames Sorry forgot to post the link https://healthunlocked.com/cure-parkinsons/posts/148823020/is-this-the-miracle-weve-all-been-waiting-for-watch-this-video
ReplyDeleteAlthough it's currently targeting PD, the researcher believes it will likely work for ET and other tremor realted conditions as well.
Tom C
Thanks for the link. I had already made a note to myself to explore vibration technology and its application to ET. The link is a goldmine of information to this technology. Thanks again!
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