Over on Reddit, sarazepeda wrote: “I’ve been taking caprylic acid, and don’t wanna jinx it… (I feel like right when something starts to help, it slowly stops helping)… but it’s been almost a week and a half now and the difference is astounding.”
Now I’m very much ‘mainstream’ in regard to the treatment of Essential Tremors, but a quick google surprised me. Caprylic acid is more commonly known as Octanoic acid. Wikipedia concluded its article with “Caprylic acid has been studied as part of a ketogenic diet to treat children with intractable epilepsy.[13] Caprylic acid is currently being researched as a treatment for essential tremor.[13][14]”.
[13] Dose-escalation study of octanoic acid in patients with essential tremor and [14] Octanoic acid in alcohol-responsive essential tremor which lead me to a study I had previously read, The Effect of Octanoic Acid on Essential Voice Tremor: A Double-Blind, Placebo-Controlled Study.
From [13] “Recently, 1-octanol has been shown to have efficacy in treating patients with essential tremor (ET). The primary metabolite of 1-octanol is octanoic acid (OA), which is now thought to be the active substance that mediates tremor suppression.”
All this leads me to a summary position: If your Essential Tremors are alcohol responsive, you can take Caprylic/Octanoic acid food supplements and get similar results without the downsides of actual alcohol consumption (maybe)!
Caveat Emptor: I am not a medical person. My background is STEM, in particular Electrical Engineering/Applied Physics. I have been formally diagnosed with Essential Tremors. I actively research ETs and potential treatments. Do your own research and come to your own conclusions.
[13], the “Dose-escalation study of octanoic acid in patients with essential tremor” was a study to determine the “maximum tolerated dose”. In this study they tested doses up to 128 mg/kg and found “most frequent AE (Adverse Event) was mild abdominal discomfort.” and “Secondary efficacy measures suggested a dose-dependent reduction of tremor.” Further, “Although our trial did not reach an MTD (maximum tolerated dose), a dose-dependent effect was demonstrated in the PK/PD (pharmacokinetics/pharmacodynamics) model as well as in secondary efficacy outcomes. Future studies are needed to explore the safety in higher dose ranges and to confirm dose-dependent efficacy in a placebo-controlled design.?
“In conclusion, our results are promising for the development of OA (Octanoic Acid) as a treatment of ET.”
There you have it. It may be effective if your ETs respond to alcohol. It’s a food supplement that is readily available at a reasonable price.
AMA: Ask Me Anything
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